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Publications

A selection of 2016 publications from members of the Centre for Antimicrobial Resistance are shown below:

1               Chalmers, JD, Dicker, A, Woodhead, M & Madhava, H 2016, 'A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults' BMC Pulmonary Medicine, vol 16, no. 1, 77. DOI: 10.1186/s12890-016-0242-0

2               Chalmers, JD, Reyes, LF, Aliberti, S & Restrepo, MI 2016, 'Empirical coverage of methicillin-resistant Staphylococcus aureus in community-acquired pneumonia: those who do not remember the past are doomed to repeat it' Clinical Infectious Diseases, vol 63, no. 8, pp. 1145-1146. DOI: 10.1093/cid/ciw464

3               Chalmers, JD 2016, 'Corticosteroids for community-acquired pneumonia: a critical view of the evidence' European Respiratory Journal, vol 48, no. 4, pp. 984-986. DOI: 10.1183/13993003.01329-2016

4               Amalakuhan, B, Habib, SA, Mangat, M, Reyes, LF, Rodriguez, AH, Hinojosa, CA, Soni, NJ, Gilley, RP, Bustamante, CA, Anzueto, A, Levine, SM, Peters, JI, Aliberti, S, Sibila, O, Chalmers, JD, Torres, A, Waterer, GW, Martin-Loeches, I, Bordon, J, Blanquer, J, Sanz, F, Marcos, PJ, Rello, J, Ramirez, J, Solé-Violán, J, Luna, CM, Feldman, C, Witzenrath, M, Wunderink, RG, Stolz, D, Wiemken, TL, Shindo, Y, Dela Cruz, CS, Orihuela, CJ & Restrepo, MI 2016, 'Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis' Cytokine, vol 88, pp. 267-273. DOI: 10.1016/j.cyto.2016.08.028

5               Wilcox, MH, Chalmers, JD, Nord, CE, Freeman, J & Bouza, E 2016, 'Role of cephalosporins in the era of Clostridium difficile infection' Journal of Antimicrobial Chemotherapy. DOI: 10.1093/jac/dkw385

6               Bellelli, G, Chalmers, JD, Sotgiu, G, Dore, S, McDonnell, MJ, Goeminne, PC, Dimakou, K, Skrbic, D, Lombi, A, Pane, F, Obradovic, D, Fardon, TC, Rutherford, RM, Pesci, A & Aliberti, S 2016, 'Characterization of bronchiectasis in the elderly' Respiratory Medicine, vol 119, pp. 13-19. DOI: 10.1016/j.rmed.2016.08.008

7               McDonnell MJ, Aliberti S, Goeminne PC, Restrepo MI, Pesci A, Dupont LJ, Fardon TC, Wilson R, Loebinger MR, Skrbic D, Obradovic D, De Soyza A, Ward C, Laffey JG, Rutherford R, Chalmers JD. Co-morbidities and the risk of mortality in patients with bronchiectasis. An international cohort study. Lancet Respiratory Medicine 2016 in press.

8               Cao, Z, Casabona, MG, Kneuper, H, Chalmers, JD & Palmer, T 2016, 'The Ess/Type VII secretion system of Staphylococcus aureus secretes a nuclease toxin that targets competitor bacteria' Nature Microbiology, vol 2, 16183. DOI: 10.1038/nmicrobiol.2016.183

9               Rodrigo-Troyano, A, Suarez-Cuartin, G, Peiró, M, Barril, S, Castillo, D, Sanchez-Reus, F, Plaza, V, Restrepo, MI, Chalmers, JD & Sibila, O 2016, 'Pseudomonas aeruginosa resistance patterns and clinical outcomes in hospitalized exacerbations of COPD' Respirology , vol 21, no. 7, pp. 1235-1242. DOI: 10.1111/resp.12825

10            Aliberti, S, Masefield, S, Polverino, E, De Soyza, A, Loebinger, MR, Menendez, R, Ringshausen, FC, Vendrell, M, Powell, P, Chalmers, JD &  on behalf of the EMBARC Study Group 2016, 'Research priorities in bronchiectasis: a consensus statement from the EMBARC Clinical Research Collaboration' European Respiratory Journal, vol 48, no. 3, pp. 632-647. DOI: 10.1183/13993003.01888-2015

11            Cillóniz, C, Torres, A, Niederman, M, van der Eerden, M, Chalmers, J, Welte, T & Blasi, F 2016, 'Community-acquired pneumonia related to intracellular pathogens' Intensive Care Medicine, vol 42, no. 9, pp. 1374-1386. DOI: 10.1007/s00134-016-4394-4

12            McDonnell, MJ, Alberti, S, Goeminne, PC, Dimakou, K, Davidson, J, Ward, C, LAffey, JG, Finch, S, Pesci, A, Dupont, LJ, Fardon, TC, Skrbic, D, Obradovic, D, Cowman, S, Loebinger, MR, Rutherford, RM, De Soyza, A & Chalmers, JD 2016, 'Multidimensional severity assessment in bronchiectasis: An analysis of 7 European cohorts.' Thorax. DOI: 10.1136/thoraxjnl-2016-208481

13            Suarez-Cuartin, G, Chalmers, JD & Sibila, O 2016, 'Diagnostic challenges of bronchiectasis' Respiratory Medicine, vol 116, pp. 70-77. DOI: 10.1016/j.rmed.2016.05.014

14            Chalmers, JD, Akram, AR, Singanayagam, A, Wilcox, MH & Hill, AT 2016, 'Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia' Journal of Infection, vol 73, no. 1, pp. 45-53. DOI: 10.1016/j.jinf.2016.04.008

15            Chalmers, JD, Dicker, A, Woodhead, M & Madhava, H 2016, 'A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults' BMC Pulmonary Medicine, vol 16, no. 1, 77. DOI: 10.1186/s12890-016-0242-0

16            Sibila, O, Garcia-Bellmunt, L, Giner, J, Rodrigo-Troyano, A, Suarez-Cuartin, G, Torrego, A, Castillo, D, Solanes, I, Mateus, EF, Vidal, S, Sanchez-Reus, F, Sala, E, Cosio, BG, Restrepo, MI, Anzueto, A, Chalmers, JD & Plaza, V 2016, 'Airway Mucin 2 is decreased in patients with severe chronic obstructive pulmonary disease with bacterial colonization' Annals of the American Thoracic Society, vol 13, no. 5, pp. 636-642. DOI: 10.1513/AnnalsATS.201512-797OC

17            Sotgiu, G, Dore, S, Chalmers, JD & Aliberti, S 2016, 'Clinical phenotypes in bronchiectasis: Right on track to develop precision medicine in respiratory diseases' International Journal of Tuberculosis and Lung Disease, vol 20, no. 5, pp. 709. DOI: 10.5588/ijtld.16.0194

18            Rae, N, Finch, S & Chalmers, JD 2016, 'Cardiovascular disease as a complication of community-acquired pneumonia' Current Opinion in Pulmonary Medicine, vol 22, no. 3, pp. 212-218. DOI: 10.1097/MCP.0000000000000261

19            Aliberti, S, Lonni, S, Dore, S, McDonnell, MJ, Goeminne, PC, Dimakou, K, Fardon, T, Rutherford, R, Pesci, A, Restrepo, MI, Sotgiu, G & Chalmers, J 2016, 'Clinical phenotypes in adult patients with bronchiectasis' European Respiratory Journal, vol 47, no. 4, pp. 1113-1122. DOI: 10.1183/13993003.01899-2015

20            Chalmers, JD, McDonnell, MJ, Rutherford, R, Davidson, J, Finch, S, Crichton, M, Dupont, L, Hill, AT, Fardon, TC, De Soyza, A, Aliberti, S & Goeminne, P 2016, 'The generalizability of bronchiectasis randomized controlled trials: a multicentre cohort study' Respiratory Medicine, vol 112, pp. 51-58. DOI: 10.1016/j.rmed.2016.01.016

21            Chalmers, JD, Aliberti, S, Polverino, E, Vendrell, M, Crichton, M, Loebinger, M, Dimakou, K, Clifton, I, van der Eerden, M, Rohde, G, Murris-Espin, M, Masefield, S, Gerada, E, Shteinberg, M, Ringshausen, F, Haworth, C, Boersma, W, Rademacher, J, Hill, AT, Aksamit, T, O'Donnell, A, Morgan, L, Milenkovic, B, Tramma, L, Neves, J, Menendez, R, Paggiaro, P, Botnaru, V, Skrgat, S, Wilson, R, Goeminne, P, De Soyza, A, Welte, T, Torres, A, Elborn, JS, Blasi, F & on behalf of EMBARC 2016, 'The EMBARC European Bronchiectasis Registry: protocol for an international observational study' ERJ Open Research, vol 2, no. 1, 00081-2015, pp. 1-9. DOI: 10.1183/23120541.00081-2015

22            Cianfanelli, FR, Alcoforado Diniz, J, Guo, M, De Cesare, V, Trost, M & Coulthurst, S 2016, 'VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System' PLoS Pathogens, vol 12, no. 6, e1005735. DOI: 10.1371/journal.ppat.1005735

23            Cianfanelli, FR, Monlezun, L & Coulthurst, SJ 2016, 'Aim, Load, Fire: The Type VI Secretion System, a Bacterial Nanoweapon' Trends in Microbiology, vol 24, no. 1, pp. 51-62. DOI: 10.1016/j.tim.2015.10.005

24            Walker, H, Patton, A, Bayne, G, Marwick, C, Sneddon, J, Davey, P, Nathwani, D & Bell, S 2016, 'Reduction in post-operative acute kidney injury following a change in antibiotic prophylaxis policy for orthopaedic surgery: an observational study' Journal of Antimicrobial Chemotherapy, vol 71, no. 9, pp. 2598-2605. DOI: 10.1093/jac/dkw166

25            Davey, PG 2016, 'Structured antibiotic 'time-out' audits as recommended by the CDC reduce antibiotic use and costs' Evidence-Based Nursing, vol 19, no. 1, pp. 24. DOI: 10.1136/eb-2014-102046

26            Dewar, S, Sienkiewicz, N, Ong, HB, Wall, RJ, Horn, D & Fairlamb, AH 2016, 'The role of folate transport in antifolate drug action in Trypanosoma brucei' Journal of Biological Chemistry. DOI: 10.1074/jbc.M116.750422

27            Baragaña, B, Norcross, NR, Wilson, C, Porzelle, A, Hallyburton, I, Grimaldi, R, Osuna-Cabello, M, Norval, S, Riley, J, Stojanovski, L, Simeons, FRC, Wyatt, PG, Delves, MJ, Meister, S, Duffy, S, Avery, VM, Winzeler, EA, Sinden, RE, Wittlin, S, Frearson, JA, Gray, DW, Fairlamb, AH, Waterson, D, Campbell, SF, Willis, P, Read, KD & Gilbert, IH 2016, 'Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy' Journal of Medicinal Chemistry. DOI: 10.1021/acs.jmedchem.6b00723

28            Roberts, AJ & Fairlamb, A 2016, 'The N-myristoylome of Trypanosoma cruzi' Scientific Reports, vol 6, 31078, pp. 1-11. DOI: 10.1038/srep31078

29            Norcross, NR, Baragana, B, Wilson, C, Hallyburton, I, Osuna-Cabello, M, Norval, S, Riley, J, Stojanovski, L, Simeons, FRC, Porzelle, A, Grimaldi, R, Wittlin, S, Duffy, S, Avery, VM, Meister, S, Sanz, L, Jimenez-Diaz, B, Angulo-Barturen, I, Ferrer, S, Santos Marinez, M, Javier Gamo, F, Frearson, JA, Gray, DW, Fairlamb, AH, Winzeler, EA, Waterson, D, Campbell, SF, Willis, P, Read, KD & Gilbert, IH 2016, 'Trisubstituted Pyrimidines as Efficacious and Fast-acting Antimalarials' Journal of Medicinal Chemistry, vol 59, no. 13, pp. 6101-6120. DOI: 10.1021/acs.jmedchem.6b00028

30            Fairlamb, AH, Gow, NAR, Matthews, KR & P. Waters, A 2016, 'Drug Resistance in Eukaryotic Microorganisms' Nature Microbiology, vol 1, no. 7, 16092. DOI: 10.1038/nmicrobiol.2016.92

31            Patterson, S, Wyllie, S, Norval, S, Stojanovski, L, Simeons, FRC, Auer, JL, Osuna-Cabello, M, Read, KD & Fairlamb, AH 2016, 'The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis' eLife, vol 5, e09744. DOI: 10.7554/eLife.09744

32            W. Gibson, M, Dewar, S, Ong, HB, Sienkiewicz, N & Fairlamb, A 2016, 'Trypanosoma brucei DHRF-TS revisited: characterisation of a bifunctional and highly unstable recombinant dihydrofolate reductase-thymidylate synthase' PLoS Neglected Tropical Diseases, vol 10, no. 5, e0004714, pp. 1-20. DOI: 10.1371/journal.pntd.0004714

33            Ballell, L, Strange, M, Cammack, N, Fairlamb, AH & Borysiewicz, L 2016, 'Open Lab as a source of hits and leads against tuberculosis, malaria and kinetoplastid diseases' Nature Reviews Drug Discovery, vol 15, no. 4, 292. DOI: 10.1038/nrd.2016.51

34            Bruhn, DF, Wyllie, S, Rodríguez-Cortés, A, Carrillo, AK, Rakesh, Guy, RK, Fairlamb, AH & Lee, RE 2016, 'Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes' Journal of Antimicrobial Chemotherapy, vol 71, no. 4, dkv417, pp. 956-963. DOI: 10.1093/jac/dkv417

35            Fleming, JR, Sastry, L, Wall, SJ, Sullivan, L & Ferguson, MAJ 2016, 'Proteomic identification of immunodiagnostic antigens for Trypanosoma vivax infections in cattle and generation of a proof-of-concept lateral flow test diagnostic device' PLoS Neglected Tropical Diseases, vol 10, no. 9, e0004977. DOI: 10.1371/journal.pntd.0004977

36            Larance, M, Kirkwood, KJ, Tinti, M, Brenes Murillo, A, Ferguson, M & Lamond, A 2016, 'Global membrane protein interactome analysis using in vivo crosslinking and MS-based protein correlation profiling' Molecular & Cellular Proteomics, vol 15, no. 7, pp. 2476-2490. DOI: 10.1074/mcp.O115.055467

37            Damerow, M, Graalfs, F, Guther, MLS, Mehlert, A, Izquierdo, L & Ferguson, MAJ 2016, 'A gene of the β3-glycosyltransferase family encodes N-acetylglucosaminyltransferase II function in Trypanosoma brucei' Journal of Biological Chemistry, vol 291, no. 26, pp. 13834-13845. DOI: 10.1074/jbc.M116.733246

38            Dacks, JB, Field, MC, Buick, R, Eme, L, Gribaldo, S, Roger, AJ, Brochier-Armanet, C & Devos, DP 2016, 'The changing view of eukaryogenesis - fossils, cells, lineages and how they all come together' Journal of Cell Science, vol 129, pp. 3695-3703. DOI: 10.1242/jcs.178566

39            Maishman, L, Obado, SO, Alsford, S, Bart, J, Chen, W-M, Ratushny, AV, Navarro, M, Horn, D, Aitchison, JD, Chait, BT, Rout, MP & Field, MC 2016, 'Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression' Nucleic Acids Research. DOI: 10.1093/nar/gkw751

40            Zoltner, M, Horn, D, de Koning, HP & Field, MC 2016, 'Exploiting the Achilles' heel of membrane trafficking in trypanosomes' Current Opinion in Microbiology, vol 34, pp. 97-103. DOI: 10.1016/j.mib.2016.08.005

41            Kalb, LC, Frederico, YCA, Boehm, C, Moreira, CMDN, Soares, MJ & Field, MC 2016, 'Conservation and divergence within the clathrin interactome of Trypanosoma cruzi' Scientific Reports, vol 6, 31212, pp. 1-12. DOI: 10.1038/srep31212

42            Klinger, CM, Ramirez-Macias, I, Herman, EK, Turkewitz, AP, Field, MC & Dacks, JB 2016, 'Resolving the homology-function relationship through comparative genomics of membrane-trafficking machinery and parasite cell biology' Molecular and Biochemical Parasitology. DOI: 10.1016/j.molbiopara.2016.07.003

43            Koreny, L & Field, MC 2016, 'Ancient eukaryotic origin and evolutionary plasticity of nuclear lamina' Genome Biology and Evolution, vol 8, no. 10, pp. 2663-2671. DOI: 10.1093/gbe/evw087

44            Flegontov, P, Butenko, A, Firsov, S, Kraeva, N, Eliáš, M, Field, MC, Filatov, D, Flegontova, O, Gerasimov, ES, Hlaváčová, J, Ishemgulova, A, Jackson, AP, Kelly, S, Kostygov, AY, Logacheva, MD, Maslov, DA, Opperdoes, FR, O'Reilly, A, Sádlová, J, Ševčíková, T, Venkatesh, D, Vlček, Č, Volf, P, Votýpka, J, Záhonová, K, Yurchenko, V & Lukeš, J 2016, 'Genome of Leptomonas pyrrhocoris: a high-quality reference for monoxenous trypanosomatids and new insights into evolution of Leishmania' Scientific Reports, vol 6, 23704. DOI: 10.1038/srep23704

45            Obado, SO, Brillantes, M, Uryu, K, Zhang, W, Ketaren, NE, Chait, BT, Field, MC & Rout, MP 2016, 'Interactome mapping reveals the evolutionary history of the nuclear pore complex' PLoS Biology, vol 14, no. 2, e1002365. DOI: 10.1371/journal.pbio.1002365

46            Heider, MR, Gu, M, Duffy, CM, Mirza, AM, Marcotte, LL, Walls, AC, Farrall, N, Hakhverdyan, Z, Field, MC, Rout, MP, Frost, A & Munson, M 2016, 'Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex' Nature Structural & Molecular Biology, vol 23, no. 1, pp. 59-66. DOI: 10.1038/nsmb.3146

47            Herrera, LJ, Brand, S, Santos, A, Nohara, LL, Harrison, J, Norcross, NR, Thompson, S, Smith, V, Lema, C, Varela-Ramirez, A, Gilbert, IH, Almeida, IC & Maldonado, RA 2016, 'Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi' PLoS Neglected Tropical Diseases, vol 10, no. 4, e0004540. DOI: 10.1371/journal.pntd.0004540

48            Gage, ZO, Vasou, A, Gray, DW, Randall, RE & Adamson, CS 2016, 'Identification of novel inhibitors of the type I interferon induction pathway using cell-based high-throughput screening' Journal of Biomolecular Screening, vol 21, no. 9, pp. 978-988. DOI: 10.1177/1087057116656314

49            De Rycker, M, Thomas, J, Riley, J, Brough, SJ, Miles, TJ & Gray, DW 2016, 'Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade' PLoS Neglected Tropical Diseases, vol 10, no. 4, e0004584. DOI: 10.1371/journal.pntd.0004584

50            Moynié, L, Hope, AG, Finzel, K, Schmidberger, J, Leckie, SM, Schneider, G, Burkart, MD, Smith, AD, Gray, DW & Naismith, JH 2016, 'A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA' Journal of Molecular Biology, vol 428, no. 1, pp. 108-120. DOI: 10.1016/j.jmb.2015.10.027

51            Hutchinson, S, Glover, L & Horn, D 2016, 'High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomes' BMC Genomics, vol 17, 806. DOI: 10.1186/s12864-016-3154-8

52            Graf, FE, Ludin, P, Arquint, C, Schmidt, RS, Schaub, N, Kunz Renggli, C, Munday, JC, Krezdorn, J, Baker, N, Horn, D, Balmer, O, Caccone, A, de Koning, HP & Mäser, P 2016, 'Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense' Cellular and Molecular Life Sciences, vol 73, no. 17, pp. 3387-3400. DOI: 10.1007/s00018-016-2173-6

53            Glover, L, Hutchinson, S, Alsford, S & Horn, D 2016, 'VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes' Proceedings of the National Academy of Sciences of the United States of America, vol 113, no. 26, pp. 7225-7230. DOI: 10.1073/pnas.1600344113

54            Duraisingh, MT & Horn, D 2016, 'Epigenetic Regulation of Virulence Gene Expression in Parasitic Protozoa' Cell Host & Microbe, vol 19, no. 5, pp. 629-640. DOI: 10.1016/j.chom.2016.04.020

55            Horn, D 2016, 'How Antiparasitic Drugs Work-And Sometimes Stop Working!' PLoS Pathogens, vol 12, no. 5, pp. e1005430. DOI: 10.1371/journal.ppat.1005430

56            Song, J, Baker, N, Rothert, M, Henke, B, Jeacock, L, Horn, D & Beitz, E 2016, 'Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2' PLoS Pathogens, vol 12, no. 2, e1005436. DOI: 10.1371/journal.ppat.1005436

57            Stewardson, AJ, Allignol, A, Beyersmann, J, Graves, N, Schumacher, M, Meyer, R, Tacconelli, E, De Angelis, G, Farina, C, Pezzoli, F, Bertrand, X, Gbaguidi-Haore, H, Edgeworth, J, Tosas, O, Martinez, JA, Ayala-Blanco, MP, Pan, A, Zoncada, A, Marwick, CA, Nathwani, D, Seifert, H, Hos, N, Hagel, S, Pletz, M, Harbarth, S & TIMBER Study Group 2016, 'The health and economic burden of bloodstream infections caused by antimicrobial-susceptible and non-susceptible Enterobacteriaceae and Staphylococcus aureus in European hospitals, 2010 and 2011: a multicentre retrospective cohort study' Eurosurveillance, vol 21, no. 33, Article 2, pp. 1-12. DOI: 10.2807/1560-7917.ES.2016.21.33.30319

58            Francis, NA, Ridd, MJ, Thomas-Jones, E, Shepherd, V, Butler, CC, Hood, K, Huang, C, Addison, K, Longo, M, Marwick, C, Wootton, M, Howe, R, Roberts, A, Haq, MI-U, Madhok, V & Sullivan, F 2016, 'A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study' Health Technology Assessment, vol 20, no. 19, pp. 1-84. DOI: 10.3310/hta20190

59            Bonnici-Mallia, M, Kanodia, AK, Rae, N & Marwick, C 2016, 'Herpes simplex encephalitis: unusual imaging appearances' BMJ Case Reports, vol 2016. DOI: 10.1136/bcr-2016-214993

60            Rae, N, Jarchow-MacDonald, A, Nathwani, D & Marwick, CA 2016, 'MRSA: treating people with infection' BMJ Clinical Evidence.

61            Burton, LA, Price, R, Barr, KE, McAuley, SM, Allen, JB, Clinton, AM, Phillips, G, Marwick, CA, McMurdo, MET & Witham, MD 2016, 'Hospital-acquired pneumonia incidence and diagnosis in older patients' Age and Ageing, vol 45, no. 1, pp. 171-174. DOI: 10.1093/ageing/afv168

62            Brink, AJ, Messina, AP, Feldman, C, Richards, GA, Becker, PJ, Goff, DA, Bauer, KA, Nathwani, D, van den Bergh, D & on behalf of the Netcare Antimicrobial Stewardship Study Alliance 2016, 'Antimicrobial stewardship across 47 South African hospitals: an implementation study' Lancet Infectious Diseases, vol 16, no. 9, pp. 1017-1025. DOI: 10.1016/S1473-3099(16)30012-3

63            Nathwani, D, Dryden, M & Garau, J 2016, 'Early clinical assessment of response to treatment of skin and soft-tissue infections: How can it help clinicians? Perspectives from Europe' International Journal of Antimicrobial Agents, vol 48, no. 2, pp. 127-136. DOI: 10.1016/j.ijantimicag.2016.04.023

64            Dickstein, Y, Nir-Paz, R, Pulcini, C, Cookson, B, Beović, B, Tacconelli, E, Nathwani, D, Vatcheva-Dobrevska, R, Rodríguez-Baño, J, Hell, M, Saenz, H, Leibovici, L & Paul, M 2016, 'Staffing for infectious diseases, clinical microbiology and infection control in hospitals in 2015: results of an ESCMID-member survey ' Clinical Microbiology and Infection. DOI: 10.1016/j.cmi.2016.06.014

65            Munnoch, JT, Widdick, D, Chandra, G, Sutcliffe, IC, Palmer, T & Hutchings, MI 2016, 'Cosmid based mutagenesis causes genetic instability in Streptomyces coelicolor, as shown by targeting of the lipoprotein signal peptidase gene' Scientific Reports, vol 6, 29495. DOI: 10.1038/srep29495

66            Zoltner, M, Ng, WMAV, Money, JJ, Fyfe, PK, Kneuper, H, Palmer, T & Hunter, WN 2016, 'EssC: domain structures inform on the elusive translocation channels in the Type VII secretion system.' Biochemical Journal, vol 473, no. 13, pp. 1941-1952. DOI: 10.1042/BCJ20160257

67            Warne, B, Harkins, CP, Harris, SR, Vatsiou, A, Stanley-Wall, N, Parkhill, J, Peacock, SJ, Palmer, T & Holden, MTG 2016, 'The Ess/Type VII secretion system of Staphylococcus aureus shows unexpected genetic diversity' BMC Genomics, vol 17, 222. DOI: 10.1186/s12864-016-2426-7

68            Jager, F, Zoltner, M, Kneuper, H, Hunter, WN & Palmer, T 2016, 'Membrane interactions and self-association of components of the Ess/Type VII secretion system of Staphylococcus aureus' FEBS Letters, vol 590, no. 3, pp. 349-357. DOI: 10.1002/1873-3468.12065

69            Francisco, AF, Jayawardhana, S, Lewis, MD, White, KL, Shackleford, DM, Chen, G, Saunders, J, Osuna-Cabello, M, Read, KD, Charman, SA, Chatelain, E & Kelly, JM 2016, 'Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage' Scientific Reports, vol 6, 35351. DOI: 10.1038/srep35351

70            Stoessel, D, Nowell, CJ, Jones, AJ, Ferrins, L, Ellis, KM, Riley, J, Rahmani, R, Read, KD, McConville, MJ, Avery, VM, Baell, JB & Creek, DJ 2016, 'Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide' Metabolomics, vol 12, no. 7, 126. DOI: 10.1007/s11306-016-1062-1

71            Connelly, K, Stevenson, C, Kneuper, H & Sargent, F 2016, 'Biosynthesis of selenate reductase in Salmonella enterica: critical roles for the signal peptide and DmsD' Microbiology-SGM. DOI: 10.1099/mic.0.000381

72            Bowman, L, Balbach, J, Walton, J, Sargent, F & Parkin, A 2016, 'Biosynthesis of Salmonella enterica [NiFe]-hydrogenase-5: probing the roles of system-specific accessory proteins' Journal of Biological Inorganic Chemistry, vol 21, no. 7, pp. 865-873. DOI: 10.1007/s00775-016-1385-4

73            Carr, SB, Evans, RM, Brooke, EJ, Wehlin, SAM, Nomerotskaia, E, Sargent, F, Armstrong, FA & Phillips, SEV 2016, 'Hydrogen activation by [NiFe]-hydrogenases' Biochemical Society Transactions, vol 44, no. 3, pp. 863-868. DOI: 10.1042/BST20160031

74            Sargent, F 2016, The Model [NiFe]-Hydrogenases of Escherichia coli. in Advances in Microbial Physiology. vol. 68, Elsevier, pp. 433-507. DOI: 10.1016/bs.ampbs.2016.02.008

75            Foulkes, JM, Deplanche, K, Sargent, F, Macaskie, LE & Lloyd, JR 2016, 'A novel aerobic mechanism for reductive palladium biomineralization and recovery by escherichia coli' Geomicrobiology Journal, vol 33, no. 3-4, pp. 230-236. DOI: 10.1080/01490451.2015.1069911

76            Wulff, P, Thomas, C, Sargent, F & Armstrong, FA 2016, 'How the oxygen tolerance of a [NiFe]-hydrogenase depends on quaternary structure' Journal of Biological Inorganic Chemistry, vol 21, no. 1, pp. 121. DOI: 10.1007/s00775-015-1327-6

77            Morris, RJ, Bromley, KM, Stanley-Wall, N & MacPhee, CE 2016, 'A phenomenological description of BslA assemblies across multiple length scales' Philosophical Transactions of the Royal Society A - Mathematical Physical and Engineering Sciences, vol 374, no. 2072, 20150131. DOI: 10.1098/rsta.2015.0131

78            Arnaouteli, S, MacPhee, CE & Stanley-Wall, N 2016, 'Just in case it rains: building a hydrophobic biofilm the Bacillus subtilis way' Current Opinion in Microbiology, vol 34, pp. 7-12. DOI: 10.1016/j.mib.2016.07.012

79            Schor, M, L. Reid , J, MacPhee, CE & Stanley-Wall, N 2016, 'The diverse structures and functions of surfactant proteins' Trends in Biochemical Sciences, vol 41, no. 7, pp. 610-620. DOI: 10.1016/j.tibs.2016.04.009

80            Warne, B, Harkins, CP, Harris, SR, Vatsiou, A, Stanley-Wall, N, Parkhill, J, Peacock, SJ, Palmer, T & Holden, MTG 2016, 'The Ess/Type VII secretion system of Staphylococcus aureus shows unexpected genetic diversity' BMC Genomics, vol 17, 222. DOI: 10.1186/s12864-016-2426-7

81            Sarathy, JP, Zuccotto, F, Hsinpin, H, Sandberg, L, Via, LE, Marriner, GA, Masquelin, T, Wyatt, P, Ray, P & Dartois, V 2016, 'Prediction of drug penetration in tuberculosis lesions' ACS Infectious Diseases, vol 2, no. 8, pp. 552-563. DOI: 10.1021/acsinfecdis.6b00051

82            Baptista-Hon, DT, Krah, A, Zachariae, U & Hales, TG 2016, 'A role for loop G in the β1 strand in GABAA receptor activation' Journal of Physiology, vol 594, no. 19, pp. 5555-5571. DOI: 10.1113/JP272463

83            Vickery, O, Machtens, J-P & Zachariae, U 2016, 'Membrane Potentials Regulating GPCRs: Insights From Experiments and Molecular Dynamics Simulation' Current Opinion in Pharmacology, vol 30, pp. 44-50. DOI: 10.1016/j.coph.2016.06.011

84            Kutzner, C, Köpfer, D, Machtens, J-P, De Groot, BL, Song, C & Zachariae, U 2016, 'Insights into the function of ion channels by computational electrophysiology simulations' Biochimica et Biophysica Acta - Biomembranes, vol 1858, no. 7, pp. 1741-1752. DOI: 10.1016/j.bbamem.2016.02.006

85            Vickery, ON, Machtens, J-P, Tamburrino, G, Seeliger, D & Zachariae, U 2016, 'Structural mechanisms of voltage sensing in G protein coupled receptors' Structure, vol 24, no. 6, pp. 997-1007. DOI: 10.1016/j.str.2016.04.007